DNAJC18

Across TCGA cell cohorts, DNAJC18 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC18-associated genes across cancer lineages are TBPL2, DPRX, and PRSS41. Each is linked with DNAJC18 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC18-to-partner and partner-to-DNAJC18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBPL2 grouped by DNAJC18-low versus DNAJC18-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC18→partner) and Y-score (partner→DNAJC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TBPL2 →	+0.107	+4.044	<.001	.004	3	1
BLOOD_Leukemia	DPRX →	+0.071	+3.475	<.001	.006	3	1
BLOOD_Leukemia	PRSS41 →	+0.063	+3.475	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.021	+3.969	<.001	.009	3	1
BLOOD_Leukemia	MYOM3 →	+0.092	+4.428	<.001	<.001	2	1
BLOOD_Leukemia	C2CD4A →	+0.039	+4.103	<.001	.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TBPL2 by DNAJC18 expression — BLOOD_Leukemia

Explore this box plot interactively →