DNAJC13

Across TCGA patient cohorts, DNAJC13 mutation is significantly associated with the RNA expression of many other genes, with 4,467 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC13-associated genes across cancer lineages are FCER1A, RGS5, and DOC2B. Each is linked with DNAJC13 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAJC13-to-partner and partner-to-DNAJC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCER1A grouped by DNAJC13-low versus DNAJC13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC13→partner) and Y-score (partner→DNAJC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FCER1A →	-0.856	-2.716	<.001	<.001	3	5
STAD	RGS5 →	-1.230	-3.459	<.001	.005	3	4
UCEC	DOC2B →	-0.748	-1.616	<.001	.001	3	4
UCEC	ATP1B2 →	-0.715	-1.610	<.001	<.001	3	4
UCEC	FAM228B →	-0.224	-1.456	.007	<.001	3	4
SKCM	ZFYVE19 →	+0.407	+3.220	.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,467 associations by consensus.

FCER1A by DNAJC13 expression — UCEC

Explore this box plot interactively →