DNAJC13

Across TCGA patient cohorts, DNAJC13 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC13-associated genes across cancer lineages are ERK2, INPP4B, and p27_pT198. Each is linked with DNAJC13 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAJC13-to-partner and partner-to-DNAJC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by DNAJC13-low versus DNAJC13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC13→partner) and Y-score (partner→DNAJC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ERK2 →	+0.174	+1.695	.003	.013	3	3
UCEC	INPP4B →	-0.229	-2.087	.010	.004	3	3
UCEC	p27_pT198 →	+0.061	+1.206	.037	.009	3	3
UCEC	PCNA →	+0.209	+1.540	<.001	.001	3	3
COAD	Shc_pY317 →	-0.230	-3.442	<.001	.004	3	3
COAD	Di-Ras3 →	-0.188	-3.000	.017	.034	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

ERK2 by DNAJC13 expression — BLCA

Explore this box plot interactively →