DNAJC13

Across TCGA cell cohorts, DNAJC13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,565 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNAJC13-associated GO terms across cancer lineages are Protein localization to chromosome, telomeric region, Regulation of early endosome to late endosome transport, and Double-strand break repair via nonhomologous end joining. Each is linked with DNAJC13 in more than 15 cancer types. Because this analysis shows association rather than direction, both DNAJC13-to-partner and partner-to-DNAJC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, telomeric region grouped by DNAJC13-low versus DNAJC13-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC13→partner) and Y-score (partner→DNAJC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, telomeric region →	+0.096	+0.542	.001	.002	3	16
STOMACH	Regulation of early endosome to late endosome transport →	+0.104	+0.785	.003	.001	3	15
OESOPHAGUS	Double-strand break repair via nonhomologous end joining →	+0.069	+0.748	.005	.005	2	15
LARGE_INTESTINE	Vacuolar transport →	+0.038	+0.437	.001	.002	3	13
LARGE_INTESTINE	Vesicle-mediated transport to the plasma membrane →	+0.049	+0.546	<.001	<.001	3	12
SKIN	Cytosolic transport →	+0.070	+0.658	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,565 associations by consensus.

Protein localization to chromosome, telomeric region by DNAJC13 expression — UPPER_AERODIGESTIVE_TRACT

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