DNAJC13

Across TCGA cell cohorts, DNAJC13 mutation is significantly associated with the RNA expression of many other genes, with 152 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAJC13-associated genes across cancer lineages are KRTAP17-1, LCE5A, and OR8K3. Each is linked with DNAJC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC13-to-partner and partner-to-DNAJC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP17-1 grouped by DNAJC13-low versus DNAJC13-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC13→partner) and Y-score (partner→DNAJC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	KRTAP17-1 →	+0.023	+4.906	<.001	.006	3	2
LUNG_SCLC	LCE5A →	+0.380	+3.099	.003	.003	3	2
CNS	OR8K3 →	+0.013	+5.754	<.001	.002	3	2
LARGE_INTESTINE	UTF1 →	+0.015	+3.047	<.001	.001	3	2
SOFT_TISSUE	TARM1 →	+0.024	+5.369	.009	.004	3	1
SOFT_TISSUE	PPIAL4F →	+0.094	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 152 associations by consensus.

KRTAP17-1 by DNAJC13 expression — OESOPHAGUS

Explore this box plot interactively →