DNAJC12

Across TCGA patient cohorts, DNAJC12 mutation is significantly associated with the RNA expression of many other genes, with 859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC12-associated genes across cancer lineages are RNA5SP414, RNA5SP419, and LINC02120. Each is linked with DNAJC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC12-to-partner and partner-to-DNAJC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by DNAJC12-low versus DNAJC12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC12→partner) and Y-score (partner→DNAJC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.602	+3.255	<.001	<.001	3	2
UCEC	RNA5SP419 →	+0.828	+3.077	<.001	<.001	3	2
SKCM	LINC02120 →	+0.021	+3.362	.009	.004	3	2
SKCM	RNU6-406P →	+0.172	+4.302	<.001	.007	3	2
SKCM	RPS21P8 →	+0.079	+4.147	<.001	.008	3	2
UCEC	ESS2 →	+0.415	+3.470	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 859 associations by consensus.

RNA5SP414 by DNAJC12 expression — UCEC

Explore this box plot interactively →