DNAJC11

Across TCGA pan-cancer cohorts, DNAJC11 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated DNAJC11 data layer compared with 21 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DNAJC11 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated DNAJC11 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

UCEC, HNSC, and SKCM are the cancer types where DNAJC11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.612	.001	34	view →
HNSC	OS	Median	IV	0.156	0.708	.007	12	view →
SKCM	OS	Median	II,III,IV	0.257	0.742	.001	9	view →
LGG	DFS	Median	All	0.110	0.833	<.001	6	view →
STAD	OS	Median	All	0.199	0.729	.036	6	view →
BLCA	DFS	Median	All	0.901	0.324	.015	6	view →
LIHC	OS	Median	II,III,IV	0.239	0.715	.035	3	view →
COAD	DFS	Median	II,III,IV	0.140	0.551	.028	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

DNAJC11–UCEC (DFS)

Open the UCEC breakdown →