DNAJC11

Across TCGA cell cohorts, DNAJC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,682 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNAJC11-associated GO terms across cancer lineages are Regulation of telomerase RNA localization to Cajal body, Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and rRNA 5'-end processing. Each is linked with DNAJC11 in more than 18 cancer types. Because this analysis shows association rather than direction, both DNAJC11-to-partner and partner-to-DNAJC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomerase RNA localization to Cajal body grouped by DNAJC11-low versus DNAJC11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC11→partner) and Y-score (partner→DNAJC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of telomerase RNA localization to Cajal body →	+0.107	+0.878	<.001	.001	3	19
LIVER	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.156	+0.670	.004	.004	3	18
LIVER	rRNA 5'-end processing →	+0.156	+0.670	.004	.004	3	18
BLOOD_Myeloma	DNA-templated DNA replication maintenance of fidelity →	+0.100	+0.893	<.001	.001	3	18
LIVER	Promoter clearance during DNA-templated transcription →	+0.144	+0.775	.001	.004	3	17
LIVER	RNA polymerase II promoter clearance →	+0.144	+0.775	.001	.004	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,682 associations by consensus.

Regulation of telomerase RNA localization to Cajal body by DNAJC11 expression — UPPER_AERODIGESTIVE_TRACT

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