DNAJB8

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAJB8 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJB8-associated genes across cancer lineages are MYOD1. Each is linked with DNAJB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB8-to-partner and partner-to-DNAJB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by DNAJB8-low versus DNAJB8-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB8→partner) and Y-score (partner→DNAJB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaMYOD1 →+0.025+4.922<.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MYOD1 by DNAJB8 expression — BLOOD_Leukemia

Box plot of MYOD1 in DNAJB8-low vs DNAJB8-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration