DNAJB8

Across TCGA pan-cancer cohorts, DNAJB8 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated DNAJB8 data layer compared with 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DNAJB8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DNAJB8 expression acts as an unfavorable survival marker, although some lineages such as CESC and UCS show a favorable association.

COAD, READ, and CESC are the cancer types where DNAJB8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.760	0.884	.001	123	view →
READ	DFS	Tertile	II,III,IV	0.368	0.705	<.001	63	view →
CESC	DFS	Tertile	All	0.858	0.707	.012	60	view →
BRCA	OS	Tertile	IV	0.360	0.841	.002	36	view →
KICH	OS	Tertile	III,IV	0.235	0.794	.004	33	view →
UCS	OS	Tertile	All	0.635	0.269	.026	28	view →
LIHC	DFS	Tertile	All	0.353	0.565	.024	21	view →
PCPG	DFS	Quartile	All	1.000	0.597	.005	19	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
LUAD	DFS	Tertile	II,III,IV	0.890	0.677	.032	12	view →
KIRP	DFS	Tertile	All	0.731	0.882	.015	6	view →
SCLC	DFS	Quartile	All	0.427	0.890	.003	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

DNAJB8–COAD (OS)

Open the COAD breakdown →