DNAJB7

Across TCGA patient cohorts, DNAJB7 mutation is significantly associated with the RNA expression of many other genes, with 830 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB7-associated genes across cancer lineages are LINC01707, LINC02522, and RN7SL196P. Each is linked with DNAJB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB7-to-partner and partner-to-DNAJB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01707 grouped by DNAJB7-low versus DNAJB7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB7→partner) and Y-score (partner→DNAJB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01707 →	+0.170	+4.693	<.001	.007	3	2
UCEC	LINC02522 →	+0.721	+2.777	<.001	<.001	3	2
BRCA	RN7SL196P →	+0.159	+7.731	<.001	.009	3	1
UCEC	PAMR1 →	-0.979	-3.684	.007	.001	3	1
UCEC	TMEM138 →	+0.273	+2.917	.007	.001	3	1
UCEC	CHEK1 →	+0.743	+2.928	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 830 associations by consensus.

LINC01707 by DNAJB7 expression — COAD

Explore this box plot interactively →