DNAJB7

Across TCGA cell cohorts, DNAJB7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,173 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJB7-associated GO terms across cancer lineages are Microtubule nucleation, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and DNA-templated DNA replication maintenance of fidelity. Each is linked with DNAJB7 in more than 16 cancer types. Because this analysis shows association rather than direction, both DNAJB7-to-partner and partner-to-DNAJB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by DNAJB7-low versus DNAJB7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB7→partner) and Y-score (partner→DNAJB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule nucleation →	+0.130	+0.153	<.001	<.001	2	17
SOFT_TISSUE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.151	+0.244	<.001	<.001	3	16
BLOOD_Leukemia	DNA-templated DNA replication maintenance of fidelity →	+0.085	+0.119	<.001	<.001	3	16
BLOOD_Leukemia	Microtubule polymerization →	+0.097	+0.132	<.001	<.001	3	15
SOFT_TISSUE	Nuclear export →	+0.123	+0.229	<.001	<.001	3	15
OVARY	Double-strand break repair →	+0.063	+0.117	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,173 associations by consensus.

Microtubule nucleation by DNAJB7 expression — BONE

Explore this box plot interactively →