DNAJB7

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAJB7 mutation is significantly associated with the mutation status of many other genes, with 1,915 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAJB7-associated genes across cancer lineages are ATP2B3, FKBP9, and SLTM. Each is linked with DNAJB7 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAJB7-to-partner and partner-to-DNAJB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP2B3 grouped by DNAJB7-low versus DNAJB7-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB7→partner) and Y-score (partner→DNAJB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTATP2B3 →+4.297+4.857.009.00913
BLOOD_LeukemiaFKBP9 →+5.894+5.321.002.00213
BLOOD_LeukemiaSLTM →+4.479+5.635<.001<.00113
BLOOD_LeukemiaZNF462 →+2.572+4.129.009.00913
BREASTWDR11 →+4.297+4.857.009.00913
BREASTMIGA2 →+5.297+5.297.004.00413
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,915 associations by consensus.

ATP2B3 by DNAJB7 expression — BREAST

Box plot of ATP2B3 in DNAJB7-low vs DNAJB7-high samples in BREAST.

Explore this box plot interactively →

Exploration