DNAJB5

Across TCGA cell cohorts, DNAJB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,744 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJB5-associated GO terms across cancer lineages are Regulation of glycolytic process through fructose-6-phosphate, Negative regulation of glycolytic process through fructose-6-phosphate, and Negative regulation of cilium assembly. Each is linked with DNAJB5 in more than 15 cancer types. Because this analysis shows association rather than direction, both DNAJB5-to-partner and partner-to-DNAJB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glycolytic process through fructose-6-phosphate grouped by DNAJB5-low versus DNAJB5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB5→partner) and Y-score (partner→DNAJB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of glycolytic process through fructose-6-phosphate →	+0.158	+1.211	.001	.006	2	16
OESOPHAGUS	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.158	+1.211	.001	.006	2	16
SOFT_TISSUE	Negative regulation of cilium assembly →	+0.101	+1.148	<.001	<.001	3	14
LARGE_INTESTINE	Tissue homeostasis →	-0.080	-0.837	<.001	<.001	3	12
LARGE_INTESTINE	Autophagosome organization →	+0.057	+0.675	<.001	.001	3	12
OVARY	Negative regulation of smoothened signaling pathway →	+0.061	+1.313	.006	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,744 associations by consensus.

Regulation of glycolytic process through fructose-6-phosphate by DNAJB5 expression — OESOPHAGUS

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