Across TCGA patient cohorts, DNAJB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,336 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAJB3-associated proteins across cancer lineages are AKR1C3, ME1, and AKR1C2. Each is linked with DNAJB3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNAJB3-to-partner and partner-to-DNAJB3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB3→partner) and Y-score (partner→DNAJB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1C3 →	+1.711	+2.313	<.001	<.001	3	6
LSCC	ME1 →	+1.039	+2.471	<.001	<.001	3	4
LSCC	AKR1C2 →	+1.856	+2.288	<.001	<.001	3	4
LSCC	AKR1C3_S129 →	+1.734	+1.883	<.001	<.001	3	4
LSCC	UGT1A6 →	+1.473	+2.528	<.001	<.001	3	4
LSCC	PNPT1 →	+0.452	+1.172	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,336 associations by consensus.

Exploration

DNAJB3 survival (RNA) · tumor vs normal (RNA) · all DNAJB3 data types