DNAJA4

Across TCGA patient cohorts, DNAJA4 mutation is significantly associated with the RNA expression of many other genes, with 2,397 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJA4-associated genes across cancer lineages are KNOP1P4, RN7SL314P, and LINC01689. Each is linked with DNAJA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJA4-to-partner and partner-to-DNAJA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KNOP1P4 grouped by DNAJA4-low versus DNAJA4-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA4→partner) and Y-score (partner→DNAJA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	KNOP1P4 →	+0.057	+5.119	<.001	.001	3	2
LIHC	RN7SL314P →	+0.121	+4.878	<.001	.005	3	2
BRCA	LINC01689 →	+0.088	+5.324	<.001	.003	3	2
SKCM	AK4P6 →	+0.105	+5.564	<.001	<.001	3	2
UCEC	FGF21 →	+0.553	+2.595	<.001	<.001	3	2
LUSC	MIR5591 →	+0.705	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,397 associations by consensus.

KNOP1P4 by DNAJA4 expression — LIHC

Explore this box plot interactively →