DNAJA4

Across TCGA cell cohorts, DNAJA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,515 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJA4-associated GO terms across cancer lineages are Autophagosome membrane docking, Regulation of mitotic spindle assembly, and Regulation of antigen processing and presentation of peptide antigen via MHC class II. Each is linked with DNAJA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both DNAJA4-to-partner and partner-to-DNAJA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome membrane docking grouped by DNAJA4-low versus DNAJA4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA4→partner) and Y-score (partner→DNAJA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Autophagosome membrane docking →	+0.129	+2.276	.006	.002	3	8
STOMACH	Regulation of mitotic spindle assembly →	+0.114	+2.749	.004	.001	3	8
OESOPHAGUS	Regulation of antigen processing and presentation of peptide antigen via MHC class II →	+1.482	+3.284	.003	<.001	3	8
LUNG_NSCLC_LUSC	Secretion by tissue →	+0.274	+2.214	<.001	<.001	3	8
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.071	+1.544	.001	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.076	+1.202	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,515 associations by consensus.

Autophagosome membrane docking by DNAJA4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →