DNAJA4

Across TCGA cell cohorts, DNAJA4 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNAJA4-associated genes across cancer lineages are ZAN, SPIC, and BTNL2. Each is linked with DNAJA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJA4-to-partner and partner-to-DNAJA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZAN grouped by DNAJA4-low versus DNAJA4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA4→partner) and Y-score (partner→DNAJA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZAN →	+0.016	+4.467	<.001	.004	3	1
LARGE_INTESTINE	SPIC →	+0.296	+4.095	<.001	.009	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CELA2B →	+0.052	+4.273	.002	.006	3	1
LARGE_INTESTINE	TEX53 →	+0.123	+4.684	<.001	.002	3	1
BLOOD_Lymphoma	GPR119 →	+0.018	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ZAN by DNAJA4 expression — LARGE_INTESTINE

Explore this box plot interactively →