DNAJA3

Across TCGA cell cohorts, DNAJA3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJA3-associated genes across cancer lineages are LIM2, TAAR6, and DCD. Each is linked with DNAJA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJA3-to-partner and partner-to-DNAJA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIM2 grouped by DNAJA3-low versus DNAJA3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA3→partner) and Y-score (partner→DNAJA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LIM2 →	+0.021	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TAAR6 →	+0.018	+4.922	<.001	.009	3	1
BLOOD_Leukemia	DCD →	+0.036	+5.969	<.001	.001	3	1
BLOOD_Leukemia	OR9I1 →	+0.013	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR10H5 →	+0.070	+4.922	<.001	.009	3	1
BLOOD_Leukemia	PRR23B →	+0.006	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

LIM2 by DNAJA3 expression — BLOOD_Leukemia

Explore this box plot interactively →