DNAJA3

Across TCGA cell cohorts, DNAJA3 mutation is significantly associated with the mutation status of many other genes, with 1,520 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAJA3-associated genes across cancer lineages are SGK1, TDO2, and GABRB2. Each is linked with DNAJA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAJA3-to-partner and partner-to-DNAJA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SGK1 grouped by DNAJA3-low versus DNAJA3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA3→partner) and Y-score (partner→DNAJA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SGK1 →	+5.894	+5.321	.002	.002	1	3
SKIN	TDO2 →	+4.239	+5.053	.007	.007	1	3
BLOOD_Leukemia	GABRB2 →	+4.309	+4.560	.007	.007	1	3
LARGE_INTESTINE	MLXIP →	+3.350	+4.584	.003	.003	1	3
BLOOD_Leukemia	PRDM15 →	+2.894	+4.432	.005	.005	1	3
CNS	APLP1 →	+4.459	+5.277	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,520 associations by consensus.

SGK1 by DNAJA3 expression — BLOOD_Leukemia

Explore this box plot interactively →