DNAI4

Across TCGA patient cohorts, DNAI4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,273 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DNAI4-associated proteins across cancer lineages are BBS2, BBS7, and DDX21. Each is linked with DNAI4 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNAI4-to-partner and partner-to-DNAI4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAI4 versus BBS2 in BRCA, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAI4→partner) and Y-score (partner→DNAI4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BBS2 →	+0.479	+0.697	<.001	<.001	3	7
BRCA	BBS7 →	+0.382	+0.744	<.001	<.001	3	7
BRCA	DDX21 →	-0.577	-0.694	<.001	<.001	3	7
UCEC	TTC21B →	+0.328	+0.813	<.001	<.001	3	7
BRCA	IFT140 →	+0.483	+0.893	<.001	<.001	3	7
GBM	IFT74 →	+0.520	+0.998	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,273 associations by consensus.

DNAI4 vs BBS2 — BRCA

Explore this scatter interactively →