DNAI1

Across TCGA patient cohorts, DNAI1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,153 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAI1-associated genes across cancer lineages are SPEF1, ADNP2, and GUCY2F. Each is linked with DNAI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAI1-to-partner and partner-to-DNAI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAI1 versus SPEF1 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAI1→partner) and Y-score (partner→DNAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+2.219	+1.249	<.001	<.001	3	3
LSCC	ADNP2 →	-0.526	-0.937	<.001	<.001	3	3
UCEC	GUCY2F →	+0.759	+0.958	<.001	<.001	3	3
UCEC	CCDC113 →	+1.368	+0.987	<.001	<.001	3	3
UCEC	RP1 →	+1.419	+0.869	<.001	<.001	3	3
UCEC	CCDC114 →	+1.792	+1.053	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,153 associations by consensus.

DNAI1 vs SPEF1 — UCEC

Explore this scatter interactively →