DNAH5

Across TCGA patient cohorts, DNAH5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,677 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAH5-associated genes across cancer lineages are KIAA2012, DNAH12, and KCNG3. Each is linked with DNAH5 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAH5-to-partner and partner-to-DNAH5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAH5 versus KIAA2012 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH5→partner) and Y-score (partner→DNAH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIAA2012 →	+1.211	+0.782	.001	.001	3	4
UCEC	DNAH12 →	+2.519	+0.794	<.001	<.001	3	4
LSCC	KCNG3 →	-0.940	-0.502	.003	.002	3	3
UCEC	SPEF1 →	+2.346	+0.910	<.001	<.001	3	3
UCEC	RP1 →	+1.438	+0.599	.001	.003	3	3
UCEC	CCDC114 →	+1.340	+0.678	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,677 associations by consensus.

DNAH5 vs KIAA2012 — UCEC

Explore this scatter interactively →