DNAH17-AS1

Across TCGA pan-cancer cohorts, DNAH17-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DNAH17-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DNAH17-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAH17-AS1 expression acts as an unfavorable survival marker, although some lineages such as THYM and OV show a favorable association.

KIRC, UVM, and COAD are the cancer types where DNAH17-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.394	0.630	<.001	162	view →
UVM	DFS	Median	All	0.412	0.732	<.001	129	view →
COAD	DFS	Median	All	0.401	0.616	<.001	80	view →
UCEC	DFS	Quartile	All	0.462	0.685	.002	56	view →
LIHC	OS	Tertile	All	0.574	0.750	<.001	50	view →
MESO	OS	Tertile	II,III,IV	0.402	0.655	.002	35	view →
ACC	DFS	Median	All	0.253	0.605	.001	28	view →
THCA	DFS	Quartile	II,III,IV	0.514	0.860	.003	16	view →
KIRP	OS	Median	II,III,IV	0.523	0.928	.011	14	view →
PAAD	OS	Tertile	All	0.276	0.511	.013	13	view →
SARC	OS	Quartile	All	0.562	0.891	<.001	11	view →
THYM	OS	Tertile	II,III,IV	1.000	0.709	.014	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

DNAH17-AS1–KIRC (DFS)

Open the KIRC breakdown →