DNAH14

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAH14 mutation is significantly associated with the RNA expression of many other genes, with 1,568 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAH14-associated genes across cancer lineages are CCDC167, GPN3, and GNL3. Each is linked with DNAH14 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAH14-to-partner and partner-to-DNAH14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH14→partner) and Y-score (partner→DNAH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCCCDC167 →+0.618+3.169.007.00633
LARGE_INTESTINEGPN3 →+0.544+2.523<.001.00333
LARGE_INTESTINEGNL3 →+0.569+2.043<.001.00133
SOFT_TISSUECCR4 →+0.042+3.222.001.00932
LARGE_INTESTINEFAM149A →+0.953+2.389.003.00632
BLOOD_LeukemiaGSC →+0.851+3.948.002.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,568 associations by consensus.

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