DNAAF4

Across TCGA patient cohorts, DNAAF4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,264 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAAF4-associated genes across cancer lineages are SH3BP1, ANKRD54, and CBY1. Each is linked with DNAAF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAAF4-to-partner and partner-to-DNAAF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAAF4 versus SH3BP1 in UCEC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF4→partner) and Y-score (partner→DNAAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SH3BP1 →	-0.385	-0.812	.002	<.001	3	1
UCEC	ANKRD54 →	+0.716	+0.690	<.001	.004	3	1
UCEC	CBY1 →	+0.660	+0.892	<.001	.001	3	1
UCEC	RSPH14 →	+1.223	+1.137	<.001	<.001	3	1
UCEC	RAB36 →	+1.130	+0.872	<.001	<.001	3	1
UCEC	MCAT →	+0.916	+0.791	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,264 associations by consensus.

DNAAF4 vs SH3BP1 — UCEC

Explore this scatter interactively →