DNAAF4

Across TCGA patient cohorts, DNAAF4 mutation is significantly associated with the RNA expression of many other genes, with 2,814 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAAF4-associated genes across cancer lineages are RNU6-271P, MIR517B, and DHRS11. Each is linked with DNAAF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAAF4-to-partner and partner-to-DNAAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by DNAAF4-low versus DNAAF4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF4→partner) and Y-score (partner→DNAAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-271P →	+0.110	+4.485	<.001	.004	3	2
SKCM	MIR517B →	+0.203	+4.485	<.001	.004	3	2
UCEC	DHRS11 →	+0.667	+4.032	<.001	<.001	3	2
SKCM	RN7SL513P →	+0.316	+3.376	<.001	<.001	3	2
SKCM	RN7SL837P →	+0.069	+3.993	<.001	.008	3	2
SKCM	OR5J7P →	+0.045	+3.993	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,814 associations by consensus.

RNU6-271P by DNAAF4 expression — SKCM

Explore this box plot interactively →