DNAAF1

Across TCGA patient cohorts, DNAAF1 mutation is significantly associated with the RNA expression of many other genes, with 1,699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAAF1-associated genes across cancer lineages are LGALS16, MIR6075, and LINC02205. Each is linked with DNAAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAAF1-to-partner and partner-to-DNAAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS16 grouped by DNAAF1-low versus DNAAF1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF1→partner) and Y-score (partner→DNAAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LGALS16 →	+0.107	+4.327	<.001	.009	3	3
LIHC	MIR6075 →	+0.330	+4.544	<.001	.009	3	2
LIHC	LINC02205 →	+0.153	+4.758	<.001	.006	3	2
BRCA	PRR13P7 →	+0.095	+5.020	.002	.009	3	2
BRCA	RPL7AP56 →	+0.055	+5.473	<.001	.005	3	2
LUAD	CENPVL1 →	+0.043	+5.912	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,699 associations by consensus.

LGALS16 by DNAAF1 expression — HNSC

Explore this box plot interactively →