DMXL1

Across TCGA patient cohorts, DMXL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,373 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DMXL1-associated proteins across cancer lineages are DMXL1_S1285, ISOC1, and PPIP5K2. Each is linked with DMXL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DMXL1-to-partner and partner-to-DMXL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMXL1 versus DMXL1_S1285 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMXL1→partner) and Y-score (partner→DMXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DMXL1_S1285 →	+0.734	+0.589	<.001	.006	3	5
BRCA	ISOC1 →	+0.363	+0.535	<.001	<.001	3	4
CCRCC	PPIP5K2 →	+0.219	+0.274	.004	.004	3	4
LUAD	SNX2 →	+0.167	+0.312	<.001	<.001	3	4
PDAC	DMXL1_S1970 →	+0.645	+0.242	.002	.005	3	4
BRCA	PCBD1 →	+0.595	+0.817	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,373 associations by consensus.

DMXL1 vs DMXL1_S1285 — BRCA

Explore this scatter interactively →