Across TCGA patient cohorts, DMWD protein abundance is significantly associated with the RNA expression of many other genes, with 4,159 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMWD-associated genes across cancer lineages are PABPC5-AS1, TRHDE, and NMUR2. Each is linked with DMWD in more than 2 cancer types. Because this analysis shows association rather than direction, both DMWD-to-partner and partner-to-DMWD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMWD→partner) and Y-score (partner→DMWD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PABPC5-AS1 →	+0.828	+0.331	<.001	.001	3	3
GBM	TRHDE →	+0.480	+0.258	<.001	<.001	3	3
UCEC	NMUR2 →	+1.323	+0.708	.003	<.001	3	2
UCEC	RNU5B-4P →	+1.009	+0.608	.004	.005	3	2
UCEC	SNORD53B →	-1.200	-0.722	<.001	<.001	3	2
GBM	DMAC1P1 →	+1.111	+0.237	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

Exploration

DMWD survival (RNA) · tumor vs normal (RNA) · all DMWD data types