Across TCGA patient cohorts, DMWD mutation is significantly associated with the RNA expression of many other genes, with 2,017 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DMWD-associated genes across cancer lineages are LINC02438, MIR3179-2, and SNORD91B. Each is linked with DMWD in more than 2 cancer types. Because this analysis shows association rather than direction, both DMWD-to-partner and partner-to-DMWD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMWD→partner) and Y-score (partner→DMWD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02438 →	+0.751	+3.798	.005	.005	3	3
BRCA	MIR3179-2 →	+0.418	+8.471	<.001	.005	3	2
UCEC	SNORD91B →	+0.303	+1.797	.008	.008	3	2
UCEC	MIR8075 →	+0.668	+1.634	<.001	.009	3	2
UCEC	LIN7C →	+0.520	+3.095	.004	<.001	3	2
UCEC	AP3S2 →	+0.305	+3.507	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,017 associations by consensus.

Exploration

DMWD survival (RNA) · tumor vs normal (RNA) · all DMWD data types