DMRTB1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DMRTB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,999 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible DMRTB1-associated GO terms across cancer lineages are Mitochondrial gene expression, Protein-RNA complex organization, and tRNA metabolic process. Each is linked with DMRTB1 in more than 10 cancer types. Because this analysis shows association rather than direction, both DMRTB1-to-partner and partner-to-DMRTB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by DMRTB1-low versus DMRTB1-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTB1→partner) and Y-score (partner→DMRTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRCMitochondrial gene expression →+0.030+0.008<.001<.001311
KIRCProtein-RNA complex organization →+0.033+0.008<.001<.001311
STADtRNA metabolic process →+0.098+0.200<.001<.001211
STADMitochondrial transport →+0.099+0.188<.001.001211
HNSCPositive regulation of cell cycle G2/M phase transition →+0.033+0.083<.001.00439
KIRCPositive regulation of DNA repair →+0.035+0.007<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,999 associations by consensus.

Mitochondrial gene expression by DMRTB1 expression — KIRC

Box plot of Mitochondrial gene expression in DMRTB1-low vs DMRTB1-high samples in KIRC.

Explore this box plot interactively →

Exploration