DMRTB1

Across TCGA cell cohorts, DMRTB1 RNA expression is significantly associated with the mutation status of many other genes, with 152 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DMRTB1-associated genes across cancer lineages are STAB1, MAGI2, and MSLN. Each is linked with DMRTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMRTB1-to-partner and partner-to-DMRTB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAB1 grouped by DMRTB1-low versus DMRTB1-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTB1→partner) and Y-score (partner→DMRTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	STAB1 →	+3.832	+0.025	.001	<.001	3	2
SOFT_TISSUE	MAGI2 →	+4.417	+0.045	.004	<.001	3	2
BLOOD_Leukemia	MSLN →	+4.475	+0.043	<.001	<.001	3	2
LUNG_NSCLC_LUAD	PIGK →	+4.887	+0.006	.009	<.001	3	2
LUNG_NSCLC_LUAD	CFTR →	+2.887	+0.003	.009	<.001	3	2
LUNG_NSCLC_LUAD	MUC5AC →	+4.887	+0.006	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 152 associations by consensus.

STAB1 by DMRTB1 expression — SOFT_TISSUE

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