DMRTB1

Across TCGA cell cohorts, DMRTB1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DMRTB1-associated genes across cancer lineages are GP9, KRTAP9-8, and SLC51B. Each is linked with DMRTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMRTB1-to-partner and partner-to-DMRTB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP9 grouped by DMRTB1-low versus DMRTB1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTB1→partner) and Y-score (partner→DMRTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GP9 →	+0.024	+4.029	.006	.009	3	1
OVARY	KRTAP9-8 →	+0.025	+4.807	<.001	.003	3	1
BLOOD_Leukemia	SLC51B →	+0.073	+3.769	<.001	.008	3	1
BLOOD_Leukemia	C18orf63 →	+0.052	+3.705	<.001	.007	3	1
LARGE_INTESTINE	SLC39A12 →	+0.090	+3.700	<.001	.004	3	1
LARGE_INTESTINE	OR13D1 →	+0.019	+2.882	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GP9 by DMRTB1 expression — OVARY

Explore this box plot interactively →