DMRT2

Across TCGA cell cohorts, DMRT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,416 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DMRT2-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, Oxidative phosphorylation, and Cellular respiration. Each is linked with DMRT2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DMRT2-to-partner and partner-to-DMRT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven ATP synthesis grouped by DMRT2-low versus DMRT2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRT2→partner) and Y-score (partner→DMRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Proton motive force-driven ATP synthesis →	+0.147	+1.054	<.001	<.001	3	8
OVARY	Oxidative phosphorylation →	+0.124	+1.015	<.001	<.001	3	8
OVARY	Cellular respiration →	+0.097	+0.872	<.001	.001	3	8
OVARY	Proton motive force-driven mitochondrial ATP synthesis →	+0.081	+0.741	<.001	<.001	3	7
OVARY	Mitochondrial electron transport, NADH to ubiquinone →	+0.079	+0.712	<.001	<.001	3	7
OVARY	ATP biosynthetic process →	+0.087	+0.743	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,416 associations by consensus.

Proton motive force-driven ATP synthesis by DMRT2 expression — OVARY

Explore this box plot interactively →