DMP1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DMP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,725 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMP1-associated proteins across cancer lineages are SPP1_S195, SPP1_S62, and CGGBP1. Each is linked with DMP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DMP1-to-partner and partner-to-DMP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMP1 versus SPP1_S195 in CCRCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMP1→partner) and Y-score (partner→DMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCSPP1_S195 →+0.962+1.030<.001<.00135
LUADSPP1_S62 →+1.385+1.180<.001<.00135
GBMCGGBP1 →-0.376-0.875<.001.00135
GBMERRFI1_S251 →+0.973+1.364<.001<.00135
LSCCPLCL2_S1113 →-0.538-0.969.003.00135
CCRCCSPP1_S234 →+1.188+0.923<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,725 associations by consensus.

DMP1 vs SPP1_S195 — CCRCC

Per-sample scatter of DMP1 vs SPP1_S195 in CCRCC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration