DMP1

Across TCGA pan-cancer cohorts, DMP1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of DMP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DMP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DMP1 is over-expressed in tumor.

HNSC, KIRC, and LUAD are the cancer types where DMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.161	<.001	12	view →
KIRC	Female	III,IV	+0.459	<.001	11	view →
LUAD	All	All	+0.172	<.001	8	view →
LUSC	All	All	+0.303	<.001	6	view →
BRCA	All	II,III,IV	+0.259	<.001	6	view →
COAD	All	All	+0.018	.001	6	view →
THCA	All	All	+0.214	<.001	5	view →
STAD	Male	II,III,IV	+0.200	<.001	5	view →
LIHC	All	All	+0.035	.010	3	view →
UCEC	All	IV	+0.165	.042	2	view →
PRAD	All	All	+0.016	.036	2	view →
CHOL	All	All	+0.111	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

DMP1–HNSC

Open the HNSC breakdown →