DMP1

Across TCGA cell cohorts, DMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 951 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible DMP1-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, RNA catabolic process, and Regulation of myoblast fusion. Each is linked with DMP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DMP1-to-partner and partner-to-DMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by DMP1-low versus DMP1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMP1→partner) and Y-score (partner→DMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Nuclear-transcribed mRNA catabolic process →	+0.076	+0.055	<.001	.003	3	8
STOMACH	RNA catabolic process →	+0.061	+0.040	<.001	.008	3	7
LUNG_NSCLC_LUAD	Regulation of myoblast fusion →	+0.061	+0.050	<.001	.001	3	6
LUNG_NSCLC_LUAD	Regulation of RNA splicing →	+0.046	+0.048	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of nuclear cell cycle DNA replication →	+0.108	+0.034	.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of telomerase RNA localization to Cajal body →	+0.076	+0.039	.002	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 951 associations by consensus.

Nuclear-transcribed mRNA catabolic process by DMP1 expression — STOMACH

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