DMBT1L1

Across TCGA patient cohorts, DMBT1L1 mutation is significantly associated with the RNA expression of many other genes, with 2,693 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DMBT1L1-associated genes across cancer lineages are RNU6-194P, MTATP6P21, and TRBV22OR9-2. Each is linked with DMBT1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMBT1L1-to-partner and partner-to-DMBT1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-194P grouped by DMBT1L1-low versus DMBT1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMBT1L1→partner) and Y-score (partner→DMBT1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-194P →	+0.316	+1.944	.005	.002	3	2
UCEC	MTATP6P21 →	+0.216	+1.867	<.001	.007	3	2
CESC	TRBV22OR9-2 →	+0.313	+5.579	<.001	.001	3	1
CESC	LINC01351 →	+0.189	+4.060	.009	.004	3	1
CESC	TRIM51EP →	+0.034	+5.579	<.001	.001	3	1
CESC	SLIT3-AS1 →	+0.288	+3.944	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,693 associations by consensus.

RNU6-194P by DMBT1L1 expression — UCEC

Explore this box plot interactively →