DMBT1L1

Across TCGA pan-cancer cohorts, DMBT1L1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated DMBT1L1 data layer compared with 3 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher DMBT1L1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DMBT1L1 expression acts as an unfavorable survival marker, although some lineages such as STAD and LGG show a favorable association.

ACC, KICH, and STAD are the cancer types where DMBT1L1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.405	0.668	.007	84	view →
KICH	OS	Tertile	All	0.752	0.981	.013	36	view →
STAD	OS	Median	All	0.743	0.600	.009	31	view →
LGG	OS	Tertile	All	0.943	0.840	.001	27	view →
BLCA	DFS	Tertile	III,IV	0.209	0.305	.013	27	view →
CHOL	DFS	Tertile	All	0.080	0.472	.003	18	view →
LIHC	DFS	Tertile	All	0.259	0.445	.016	15	view →
KIRP	DFS	Tertile	All	0.967	0.895	.037	15	view →
MESO	OS	Tertile	All	0.279	0.576	.029	9	view →
PAAD	OS	Tertile	All	0.301	0.500	.015	9	view →
KIRC	DFS	Tertile	III,IV	0.326	0.527	.024	8	view →
PRAD	OS	Tertile	All	0.970	0.994	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

DMBT1L1–ACC (OS)

Open the ACC breakdown →