DMAP1

Across TCGA cell cohorts, DMAP1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DMAP1-associated genes across cancer lineages are PNLIPRP1 and KRTAP5-4. Each is linked with DMAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMAP1-to-partner and partner-to-DMAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNLIPRP1 grouped by DMAP1-low versus DMAP1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAP1→partner) and Y-score (partner→DMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PNLIPRP1 →	+0.026	+6.022	<.001	.001	3	2
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PNLIPRP1 by DMAP1 expression — SKIN

Explore this box plot interactively →