DLX4

Across TCGA pan-cancer cohorts, DLX4 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated DLX4 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DLX4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DLX4 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

UCEC and GBM are the cancer types where DLX4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.890	1.000	.009	14	view →
GBM	OS	Median	All	0.959	0.799	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DLX4–UCEC (OS)

Open the UCEC breakdown →