DLK2

Across TCGA patient cohorts, DLK2 mutation is significantly associated with the RNA expression of many other genes, with 399 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLK2-associated genes across cancer lineages are FCF1P3, RN7SL456P, and RNU6-906P. Each is linked with DLK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLK2-to-partner and partner-to-DLK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCF1P3 grouped by DLK2-low versus DLK2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLK2→partner) and Y-score (partner→DLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FCF1P3 →	+0.153	+4.470	<.001	.005	3	2
LUSC	RN7SL456P →	+0.164	+6.578	.002	.001	3	2
SKCM	RNU6-906P →	+0.345	+4.513	<.001	.009	3	2
SKCM	RNA5SP340 →	+0.479	+5.034	<.001	.002	3	2
SKCM	LINC02439 →	+0.106	+5.797	<.001	.001	3	2
UCEC	LINC02275 →	+0.222	+3.603	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 399 associations by consensus.

FCF1P3 by DLK2 expression — SKCM

Explore this box plot interactively →