DLK2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DLK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,987 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DLK2-associated GO terms across cancer lineages are RNA localization, Establishment of RNA localization, and Positive regulation of podosome assembly. Each is linked with DLK2 in more than 10 cancer types. Because this analysis shows association rather than direction, both DLK2-to-partner and partner-to-DLK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by DLK2-low versus DLK2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLK2→partner) and Y-score (partner→DLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONERNA localization →+0.088+0.911<.001<.001311
BONEEstablishment of RNA localization →+0.115+1.219<.001<.001310
BREASTPositive regulation of podosome assembly →+1.351+1.184<.001<.001310
OESOPHAGUSPositive regulation of termination of DNA-templated transcription →+0.177+2.896<.001<.001310
OESOPHAGUSPositive regulation of termination of RNA polymerase II transcription →+0.177+2.896<.001<.001310
BONENucleic acid transport →+0.119+1.066<.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,987 associations by consensus.

RNA localization by DLK2 expression — BONE

Box plot of RNA localization in DLK2-low vs DLK2-high samples in BONE.

Explore this box plot interactively →

Exploration