Across TCGA patient cohorts, DLK1 mutation is significantly associated with the RNA expression of many other genes, with 1,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLK1-associated genes across cancer lineages are MIR4667, LRR1, and CAPZB. Each is linked with DLK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DLK1-to-partner and partner-to-DLK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLK1→partner) and Y-score (partner→DLK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MIR4667 →	+0.346	+3.855	<.001	.002	3	3
UCEC	LRR1 →	+0.573	+2.321	.001	.001	3	3
UCEC	CAPZB →	+0.287	+2.275	.004	.005	3	3
LUAD	SNRPD1 →	+0.580	+3.520	<.001	.002	3	3
UCEC	ZFP3 →	-0.698	-1.925	.001	.005	3	3
UCEC	ACD →	+0.412	+2.423	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,258 associations by consensus.

Exploration

DLK1 survival (RNA) · tumor vs normal (RNA) · all DLK1 data types