DLGAP5

Across TCGA patient cohorts, DLGAP5 mutation is significantly associated with the RNA expression of many other genes, with 4,902 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLGAP5-associated genes across cancer lineages are RNU6-13P, MIR1264, and MIR98. Each is linked with DLGAP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both DLGAP5-to-partner and partner-to-DLGAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-13P grouped by DLGAP5-low versus DLGAP5-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP5→partner) and Y-score (partner→DLGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-13P →	+0.464	+5.025	<.001	.002	3	4
BRCA	MIR1264 →	+0.229	+7.473	<.001	.007	3	3
UCEC	MIR98 →	+0.214	+2.046	<.001	.001	3	3
UCEC	RN7SL248P →	+0.046	+2.768	<.001	.002	3	3
BRCA	SNORD115-12 →	+0.284	+7.473	<.001	.007	3	3
BRCA	MIR548F1 →	+0.281	+7.473	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,902 associations by consensus.

RNU6-13P by DLGAP5 expression — HNSC

Explore this box plot interactively →