DLGAP5

Across TCGA cell cohorts, DLGAP5 mutation is significantly associated with the mutation status of many other genes, with 2,439 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DLGAP5-associated genes across cancer lineages are GAS7, RASAL3, and KDM2B. Each is linked with DLGAP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both DLGAP5-to-partner and partner-to-DLGAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAS7 grouped by DLGAP5-low versus DLGAP5-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP5→partner) and Y-score (partner→DLGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GAS7 →	+5.614	+5.044	.003	.003	1	4
OVARY	RASAL3 →	+4.415	+4.977	.007	.007	1	3
LARGE_INTESTINE	KDM2B →	+1.739	+2.600	.003	.003	1	3
LARGE_INTESTINE	TOP2A →	+2.146	+2.321	.008	.008	1	3
LARGE_INTESTINE	ENAM →	+2.632	+2.632	.003	.003	1	3
OVARY	ABCA5 →	+4.415	+4.977	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,439 associations by consensus.

GAS7 by DLGAP5 expression — CNS

Explore this box plot interactively →