Across TCGA patient cohorts, DLGAP2 mutation is significantly associated with the total protein of many other genes, with 72 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLGAP2-associated genes across cancer lineages are ATM, 4E-BP1, and FoxM1. Each is linked with DLGAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DLGAP2-to-partner and partner-to-DLGAP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP2→partner) and Y-score (partner→DLGAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.606	-1.788	<.001	<.001	3	4
UCEC	4E-BP1 →	+0.296	+2.459	<.001	<.001	3	4
UCEC	FoxM1 →	+0.169	+1.044	.011	.014	3	3
UCEC	FOXO3a_pS318_S321 →	-0.080	-1.744	.013	<.001	3	3
UCEC	PTEN →	-0.298	-1.765	.003	.011	3	3
UCEC	C-Raf →	+0.124	+1.378	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

Exploration

DLGAP2 survival (RNA) · tumor vs normal (RNA) · all DLGAP2 data types