Across TCGA cell cohorts, DLGAP2 mutation is significantly associated with the RNA expression of many other genes, with 739 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DLGAP2-associated genes across cancer lineages are PIP, EMC9, and KRT85. Each is linked with DLGAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLGAP2-to-partner and partner-to-DLGAP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP2→partner) and Y-score (partner→DLGAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	PIP →	+0.121	+3.584	<.001	.008	3	2
BLOOD_Leukemia	EMC9 →	+0.619	+3.351	.005	.003	3	2
BLOOD_Leukemia	KRT85 →	+0.018	+3.124	<.001	.004	3	2
BLOOD_Leukemia	SPZ1 →	+0.014	+2.786	.002	.009	3	2
BLOOD_Leukemia	FAM9A →	+0.007	+3.124	<.001	.004	3	2
LARGE_INTESTINE	NUP88 →	+0.479	+3.321	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 739 associations by consensus.

Exploration

DLGAP2 survival (RNA) · tumor vs normal (RNA) · all DLGAP2 data types