DLGAP1

Across TCGA cell cohorts, DLGAP1 mutation is significantly associated with the RNA expression of many other genes, with 727 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DLGAP1-associated genes across cancer lineages are OR10AC1, SPATA48, and C10orf71. Each is linked with DLGAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLGAP1-to-partner and partner-to-DLGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10AC1 grouped by DLGAP1-low versus DLGAP1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP1→partner) and Y-score (partner→DLGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10AC1 →	+0.016	+3.103	<.001	.004	3	2
CNS	SPATA48 →	+0.027	+5.357	<.001	.001	3	1
CNS	C10orf71 →	+0.006	+5.566	.004	<.001	3	1
CNS	OR5M8 →	+0.017	+4.754	<.001	.005	3	1
CNS	FCAR →	+0.035	+4.472	<.001	.004	3	1
CNS	SLC22A24 →	+0.022	+5.357	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 727 associations by consensus.

OR10AC1 by DLGAP1 expression — SKIN

Explore this box plot interactively →